Probing the structure of 'hematoporphyrin derivative' via fluorescence and absorbance spectroscopy.
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چکیده
منابع مشابه
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15 صفحه اولProbing the structure and stability of the tumor-localizing derivative of hematoporphyrin by reductive cleavage with LiAlH4.
A procedure involving the use of the reducing agent lithium aluminum hydride (LiAlH4) has been designed to explore the nature of the oligomer linkages in the tumor-localizing component of hematoporphyrin derivative (HPD). High-performance liquid chromatography and fast-atom bombardment mass spectrometry were used to determine the reduction products. The results are consistent with a structure w...
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Fluorescence studies of hematoporphyrin derivative in normal and malignant rat tissue.
Laser-induced fluorescence in rat tissue was studied during the uptake and clearing period of i.v.-injected hematoporphyrin derivative. A malignant rat tumor and normal tissue of 20 different kinds from the tumor-bearing animals were investigated. A pulsed nitrogen laser (337 nm) was used in conjunction with an optical multichannel analyzer system, in which the whole fluorescence light distribu...
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ژورنال
عنوان ژورنال: Journal of the Spectroscopical Society of Japan
سال: 1990
ISSN: 1884-6785,0038-7002
DOI: 10.5111/bunkou.39.164